| Item Type | Name |
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Concept
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Bone Marrow Cells
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Concept
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Carcinoma, Squamous Cell
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Concept
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Cell Communication
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Concept
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Cell Differentiation
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Concept
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Cell Movement
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Concept
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Carcinoma, Renal Cell
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Concept
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Cell Division
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Concept
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Cell Separation
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Concept
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Cell Cycle
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Concept
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Dendritic Cells
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Concept
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Hematopoietic Stem Cells
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Concept
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HeLa Cells
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Concept
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Receptors, Cell Surface
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Concept
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Stem Cells
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Concept
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Hematopoietic Stem Cell Transplantation
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Concept
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Th1 Cells
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Concept
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Cell Culture Techniques
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Concept
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Tumor Cells, Cultured
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Concept
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Cell Adhesion Molecules
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Concept
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PC12 Cells
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Concept
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3T3 Cells
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Concept
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Stem Cell Transplantation
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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Cell Proliferation
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Concept
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Th2 Cells
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Concept
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Genes, T-Cell Receptor
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Concept
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Jurkat Cells
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Concept
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Single-Cell Analysis
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Concept
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HEK293 Cells
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Concept
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Natural Killer T-Cells
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Concept
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Cell Engineering
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Concept
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Cell Death
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Concept
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Killer Cells, Lymphokine-Activated
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Concept
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HL-60 Cells
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Concept
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K562 Cells
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Concept
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NK Cell Lectin-Like Receptor Subfamily A
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Concept
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Programmed Cell Death 1 Receptor
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Concept
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Cell Line, Tumor
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Concept
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T Cell Transcription Factor 1
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Concept
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Cell Line
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Concept
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Cell Survival
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Concept
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Cells, Cultured
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Concept
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Receptors, Antigen, T-Cell
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Concept
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Neoplastic Stem Cells
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Academic Article
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A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition.
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Academic Article
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Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy.
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Academic Article
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MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro.
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Academic Article
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Active Immunotherapy of Cancer.
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Academic Article
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CTLA4 blockade broadens the peripheral T-cell receptor repertoire.
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Academic Article
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Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma.
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Academic Article
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Exposure to a histone deacetylase inhibitor has detrimental effects on human lymphocyte viability and function.
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Academic Article
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The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations.
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Academic Article
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Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer.
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Academic Article
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A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.
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Academic Article
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WHSC1/NSD2 regulates immune infiltration in prostate cancer.
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Academic Article
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CTLA4 blockade increases Th17 cells in patients with metastatic melanoma.
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Academic Article
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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
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Academic Article
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Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.
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Academic Article
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A rare population of tumor antigen-specific CD4+CD8+ double-positive aß T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells.
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Academic Article
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Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy.
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Academic Article
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HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice.
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Academic Article
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Cellular Immunotherapy in the Treatment of Hematopoietic Malignancies.
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Academic Article
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The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.
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Academic Article
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Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.
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Academic Article
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Rapid Construction of Antitumor T-cell Receptor Vectors from Frozen Tumors for Engineered T-cell Therapy.
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Academic Article
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BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.
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Academic Article
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Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.
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Academic Article
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Natural killer T cells in advanced melanoma patients treated with tremelimumab.
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Academic Article
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Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses.
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Academic Article
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Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models.
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Academic Article
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Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines.
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Academic Article
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Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses.
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Academic Article
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Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy.
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Academic Article
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Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
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Academic Article
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Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
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Academic Article
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Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release.
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Academic Article
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Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
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Academic Article
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Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
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Academic Article
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Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression.
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Academic Article
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Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice.
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Academic Article
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Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.
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Academic Article
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A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies.
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Academic Article
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Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC.
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Academic Article
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CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.
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Academic Article
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The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity.
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Academic Article
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Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect.
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Academic Article
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Potent maturation of monocyte-derived dendritic cells after CD40L lentiviral gene delivery.
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Academic Article
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siRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide.
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Academic Article
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Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.
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Academic Article
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The use of lentiviral vectors in gene therapy of leukemia: combinatorial gene delivery of immunomodulators into leukemia cells by state-of-the-art vectors.
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Academic Article
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Analysis of the value of empiric vancomycin administration in febrile neutropenia occurring after autologous peripheral blood stem cell transplants.
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Academic Article
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Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors.
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Academic Article
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RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
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Academic Article
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Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8(+) T cell responses.
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Academic Article
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Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer.
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Academic Article
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T cell receptor (TCR)-transgenic CD8 lymphocytes rendered insensitive to transforming growth factor beta (TGFß) signaling mediate superior tumor regression in an animal model of adoptive cell therapy.
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Academic Article
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Immune rejection in a humanized model of murine prostate cancer.
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Academic Article
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Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.
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Academic Article
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Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
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Academic Article
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Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
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Academic Article
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Immunosensitization with a Bcl-2 small molecule inhibitor.
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Academic Article
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Isolation of cDNAs that cover the entire coding region of a novel human protein D40.
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Academic Article
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Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer.
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Academic Article
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Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.
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Academic Article
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Inhibition of Alzheimer's amyloid-beta peptide-induced reduction of mitochondrial membrane potential and neurotoxicity by gelsolin.
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Academic Article
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Adoptive cell transfer of T-cell receptor-engineered lymphocytes: lessons from recent modeling.
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Academic Article
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Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition.
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Academic Article
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Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells.
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Academic Article
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Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers.
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Academic Article
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Making dendritic cells from the inside out: lentiviral vector-mediated gene delivery of granulocyte-macrophage colony-stimulating factor and interleukin 4 into CD14+ monocytes generates dendritic cells in vitro.
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Academic Article
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Engineered microenvironment for the study of myofibroblast mechanobiology.
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Academic Article
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CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer.
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Academic Article
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Engineering tumor stromal mechanics for improved T cell therapy.
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Academic Article
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Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
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Academic Article
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Correction to: Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
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Academic Article
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
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Concept
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Myeloid-Derived Suppressor Cells
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Concept
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Cell- and Tissue-Based Therapy
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Academic Article
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Implementation of a gene therapy education initiative by the ASGCT and Muhimbili University of Health and Allied Sciences.
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